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Source: http://twitter.com/nprfreshair/statuses/222388588967505921
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Tuesday, July 10, 2012
Elite Poperdido ? Home Improvement team
Painting Louisville KY Some homeowners cringe at the thought of painting. It all starts with the color samples which one should you choose? After you have picked out a color you must then make sure you have all the necessary items. You must get drop cloths, the right kind of tape, the right amount of paint and the right tools. If you do not already have these tools, you may want to hire a Thinking of painting a room? Make sure you invest not only the proper skills and knowledge, but also the correct tools to begin your paint job. You will need quality paint brushes, rollers, paint tins, tape, and drop cloths. Remember clean tools are happy tools. Be certain you continually clean your brushes. Having the correct tools will allow you to complete your paint job with care and professionalism.
Source: http://www.eltiempoperdido.net/?p=5990
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Cruise, Holmes reach settlement in divorce case
NEW YORK (AP) ? Tom Cruise and Katie Holmes reached a settlement on Monday, legally sorting out their divorce with the same speed that kicked off their much-scrutinized romance seven years ago.
Just as Hollywood was settling in for what was expected to be a long and nasty separation, lawyers for the couple said the pair settled less than two weeks after Holmes unexpectedly filed for divorce.
"The case has been settled and the agreement has been signed," Holmes attorney Jonathan Wolfe said in a statement. Cruise's rep Amanda Lundberg confirmed the settlement.
Representatives for Holmes and Cruise declined to elaborate on the agreement.
"We are thrilled for Katie and her family and are excited to watch as she embarks on the next chapter of her life," the statement from Holmes' attorney said. "We thank Tom's counsel for their professionalism and diligence that helped bring about this speedy resolution."
In a joint statement, Cruise, 50, and Holmes, 33, asked for privacy for their family with 6-year-old daughter Suri.
"We are committed to working together as parents to accomplish what is in our daughter Suri's best interests. We want to keep matters affecting our family private and express our respect for each other's commitment to each of our respective beliefs and support each other's roles as parents," read the statement from Lundberg and Holmes representative Nanci Ryder.
The resolution was notably quick, particularly in Hollywood terms. By way of comparison, Kim Kardashian and Kris Humphries are still negotiating a divorce for an August 2011 marriage that lasted less than three months.
"A quick settlement indicates that they were able to agree that they'll both do some co-parenting," said Steve Mindel, a managing partner in the Los Angeles firm Feinberg, Mindel, Brandt and Klein who has handled bi-coastal divorce cases.
Mindel said the next step would be for Holmes or Cruise to file to have their status changed to divorced, but that the actual financial and child custody details won't get filed in court unless there's some later dispute.
The rapid settlement saves the couple from a public battle that was sure to be covered vigorously by the celebrity news media, which had already shifted into hyper-drive.
In the already voluminous tabloid reporting, Holmes had been portrayed with overwhelmingly more sympathy. The emerging narrative, whether true or not, was of a locked-away Holmes breaking free from the servitude of a strange, corrupting marriage.
Us Weekly reported that the couple "fought viciously" over Scientology parenting. The Daily News trumpeted Holmes entering "a new phase." A TMZ headline blared "Tom treated me like a robot."
That may also be the most convenient view of a relationship that even at its start spawned "Free Katie!" T-shirts. In 2005, the couple publically announced their relationship in Rome, famously celebrated it on "The Oprah Winfrey Show" and got engaged on the Eiffel Tower in Paris. They were wed in Nov. 2006 at a castle in Bracciano, Italy.
Cruise's lawyer Bert Fields has said they were letting "the other side play the media until they wear everyone out." The Church of Scientology, too, didn't want to be portrayed as the schism between the couple.
The quick settlement and joint statement may put out some of that fire.
"I don't think either of these high-profile celebrities want their dirty laundry aired in technically a public forum," said Russell I. Marnell, an East Meadow, N.Y.-based divorce lawyer who's also licensed in California. "Those kind of factors certainly would lend themselves to try to encourage a resolution."
Cruise has two children with his previous wife, Nicole Kidman. The actor was also previously married to Mimi Rogers. This was Holmes' first marriage.
Their divorce case lasted less than two weeks, but Mindel said that's not uncommon for high-profile breakups: "There's too many incentives on both sides of the equation for settlement."
When actress-singer LeAnn Rimes' husband filed for divorce in December 2009, it only took a day before the couple filed a judgment. Actor-comedian Russell Brand's divorce from singer Katy Perry took a little over a month to resolve, while director Cameron Crowe and singer-guitarist Nancy Wilson resolved their 2010 divorce in less than three months.
Cruise and Holmes may have saved more than just their dignity by not fighting out their divorce in court. A drawn-out custody battle would have likely cost more than a million dollars in legal fees.
"What jumps out at me is how quickly they were able to resolve a multi-million dollar (financial case) and custody issues," likely to be particularly complicated for a couple whose work can take them all over the world, said Paul Talbert, a partner in a New York City matrimonial-law firm that isn't involved in the case.
Said Mindel: "The question's going to be did they have enough time to flesh out how they're going to resolve future disputes."
___
AP Entertainment Writer Anthony McCartney in Los Angeles and Jennifer Peltz in New York contributed to this report.
Source: http://news.yahoo.com/cruise-holmes-reach-settlement-divorce-case-172807094.html
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Tuesday, July 3, 2012
Asian stocks inch higher on Europe optimism
SINGAPORE (AP) ? Asian stock markets inched higher Monday amid continued optimism over Europe's moves to ease its debt crisis and economic malaise.
Japan's Nikkei 225 index rose 0.2 percent to 9,020.93 and South Korea's Kospi gained 0.2 percent to 1,857.26. Australia's S&P/ASX 200 index added 1.1 percent to 4,140. China's Shanghai Composite index shed 0.3 percent to 2,218.14.
Markets in Hong Kong were closed Monday to commemorate the hand-over of the territory to China in 1997.
Leaders of the 27 European Union countries said after a meeting Friday that they would seek to centralize regulation of European banks and, if necessary, bail them out directly, instead of funneling loans through governments that already have too much debt.
The EU said it also plans to ease borrowing costs for Italy and Spain, the euro region's third- and fourth-largest economies, stop mandating painful budget cuts to every country in need of emergency financial aid and tie their budgets, currency and governments more tightly.
Investors will be closely watching as EU finance ministers hash out the details of these plans over the next two weeks.
Some analysts expect the European Central Bank and the Bank of England to cut lending rates this week in a bid to spur economic growth.
"We look this week for renewed easing by the ECB and BoE in an environment of very soft business confidence," Barclays said in a report. "The primary factor behind weak global confidence is weakness in EU demand."
Trading volume in the U.S. will likely be light this week amid the Independence Day holiday on Wednesday.
Global stock and commodity markets soared Friday amid EU optimism. The Dow Jones industrial average closed up 2.2 percent at 12,880.09. The Standard & Poor's 500 index rose 2.5 percent to 1,362.16. The Nasdaq composite average jumped 3 percent to 2,935.05.
Benchmark oil for August delivery was down $1.26 to $83.70 a barrel in electronic trading on the New York Mercantile Exchange. The contract soared $7.27 to close at $84.96 in New York on Friday.
In currencies, the euro fell to $1.2632 from $1.2646 Friday in New York. The dollar rose to 79.85 yen from 79.82 yen.
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Rare leukemia-causing protein discovered
ScienceDaily (July 2, 2012) ? Researchers at the University of Cincinnati Hoxworth Blood Center have discovered a new gene target for leukemia therapy.
These findings, slated for the July 26, 2012 print issue of Blood, the journal of the American Society of Hematology, could lead to cellular targets for a patient population that otherwise may not have desirable outcomes and could potentially stop the onset of leukemia before it begins.
A team led by Jose Cancelas, MD, PhD, an associate professor of pediatrics at the UC College of Medicine and director of the research division at Hoxworth Blood Center, found that by inhibiting in animal models the protein Vav3, which controls cell signaling, the development of this leukemia -- known as BCR-ABL lymphoid leukemia -- is delayed.
"Despite advances in the treatment of this disease, the outcome of patients with this type of leukemia is very poor because it develops resistance to standard therapies," he says. "We found that the genetic deficiency of Vav3 delays the formation of leukemia by impairing the signals from BCR-ABL and the overproduction of leukemic cells. In doing this, it also allows the standardized therapies, or BCR-ABL inhibitors, to work."
Cancelas says this finding could lead to new multi-targeted therapies where Vav3 activity is related to the formation of leukemia.
"In collaboration with Dr. Nicolas Nassar, associate professor of pediatrics at UC and a physician in the division of experimental hematology at Cincinnati Children's Hospital Medical Center, we are now trying to find chemicals with Vav3 inhibitory activity," he says. "With this knowledge, we may be able to develop a therapy that can greatly improve the lives of patients facing leukemia."
Other authors of this multinational study are Kyung Hee Chang and Susan Dunn from Hoxworth Blood Center; and Yi Zheng, John Perentesis, Abel Sanchez-Aguilera, Amitava Sengupta, Malav Madhu, Ashley Ficker, Rebecca Santho and Ashley Kuenzi from Cincinnati Children's. Collaborators also include David Williams (Boston Children's Hospital, Harvard Medical School), Michael Deininger (University of Utah), Xose Bustelo (University of Salamanca, Spain) and Xabier Agirre (University of Navarra, Spain).
This study was funded by the National Heart, Lung and Blood Institute of the National Institutes of Health, the United States Department of Defense, Alex's Lemonade Stand Foundation and Cancer Free Kids Foundation.
Continuation of this study has been recently funded by the Leukemia and Lymphoma Society of North America.
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The above story is reprinted from materials provided by University of Cincinnati Academic Health Center.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- K. H. Chang, A. Sanchez-Aguilera, S. Shen, A. Sengupta, M. N. Madhu, A. M. Ficker, S. K. Dunn, A. M. Kuenzi, J. L. Arnett, R. A. Santho, X. Agirre, J. P. Perentesis, M. W. Deininger, Y. Zheng, X. R. Bustelo, D. A. Williams, J. A. Cancelas. Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation and survival. Blood, 2012; DOI: 10.1182/blood-2011-06-361709
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/_SpjPl3c0Os/120702172815.htm
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Monday, July 2, 2012
APNewsBreak: Evidence of 'God particle' found
FILE - In this May 20, 2011 file photo, a physicist explains the ATLAS experiment on a board at the European Center for Nuclear Research, CERN, outside Geneva, Switzerland. The illustration shows how the long-presumed Higgs boson particle is thought to look like. Scientists at CERN plan to make an announcement on Wednesday, July 4, 2012 about their hunt for the elusive sub-atomic particle. Physicists have said previously they are increasingly confident that they are closing in on it based on hints at its existence hidden away in reams of data. (AP Photo/Anja Niedringhaus, File)
FILE - In this May 20, 2011 file photo, a physicist explains the ATLAS experiment on a board at the European Center for Nuclear Research, CERN, outside Geneva, Switzerland. The illustration shows how the long-presumed Higgs boson particle is thought to look like. Scientists at CERN plan to make an announcement on Wednesday, July 4, 2012 about their hunt for the elusive sub-atomic particle. Physicists have said previously they are increasingly confident that they are closing in on it based on hints at its existence hidden away in reams of data. (AP Photo/Anja Niedringhaus, File)
FILE - In this May 20, 2011 file photo, a wall painting by artist Josef Kristofoletti is seen at the Atlas experiment site at the European Center for Nuclear Research, CERN, outside Geneva, Switzerland. The painting shows how a Higgs boson may look. On Wednesday, July 4, 2012, CERN plans to announce the status of their long-running hunt for the elusive subatomic particle, whose existence has only been presumed until now. (AP Photo/Anja Niedringhaus)
GENEVA (AP) ? Scientists believe the "God particle" that might explain the underpinnings of the universe is real, and they are about to present their evidence to the world.
Physicists at the world's biggest atom smasher plan to announce Wednesday that they have nearly confirmed the primary plank of a theory that could shape the scientific understanding of all matter.
The idea is much like gravity and Isaac Newton's discovery: It was there all the time before Newton explained it. But now scientists know what it is and can put that knowledge to further use.
The focus of the excitement is the Higgs boson, a subatomic particle that, if confirmed, could help explain why matter has mass, which combines with gravity to give an object weight.
Researchers at the European Organization for Nuclear Research, or CERN, say that they have compiled vast amounts of data that show the footprint and shadow of the particle ? all but proving it exists, even though it has never actually been glimpsed.
But two independent teams of physicists are cautious after decades of work and billions of dollars spent. They don't plan to use the word "discovery." They say they will come as close as possible to a "eureka" announcement without uttering a pronouncement as if from the scientific mountaintop.
"I agree that any reasonable outside observer would say, 'It looks like a discovery,'" said British theoretical physicist John Ellis, a professor at King's College London who has worked at CERN since the 1970s. "We've discovered something which is consistent with being a Higgs."
CERN's atom smasher, the $10 billion Large Hadron Collider on the Swiss-French border, has been creating high-energy collisions of protons to investigate dark matter, antimatter and the creation of the universe, which many theorize occurred in a massive explosion known as the Big Bang.
The phrase "God particle," coined by Nobel Prize-winning physicist Leon Lederman, is used by laymen, not physicists, more as an explanation for how the subatomic universe works than how it all started.
Rob Roser, who leads the search for the Higgs boson at the Fermilab in Chicago, said: "Particle physicists have a very high standard for what it takes to be a discovery," and he thinks it is a hair's breadth away. Roser compared the results that scientists will announce Wednesday to finding the fossilized imprint of a dinosaur: "You see the footprints and the shadow of the object, but you don't actually see it."
Fermilab, whose competing atom smasher reported its final results Monday after shutting down last year, said its data doesn't settle the question of the Higgs boson, but it came tantalizingly close.
"It's a real cliffhanger," said Gregorio Bernardi, a physicist at the University of Paris who helped lead one of the main experiments at Fermilab. He cited "strong indications of the production and decay of Higgs bosons" in some of their observations.
Fermilab theorist Joseph Lykken said the Higgs boson "gets at the center, for some physicists, of why the universe is here in the first place."
Though an impenetrable concept to many, the Higgs boson has until now been just that ? a concept intended to explain a riddle: How were subatomic particles, such as electrons, protons and neutrons, themselves formed? What gives them their mass?
The answer came in a theory first proposed by Scottish physicist Peter Higgs and others in the 1960s. It envisioned an energy field where particles interact with a key particle, the Higgs boson.
The idea is that other particles attract Higgs bosons and the more they attract, the bigger their mass will be. Some liken the effect to a ubiquitous Higgs snowfield that affects other particles traveling through it depending on whether they are wearing, metaphorically speaking, skis, snowshoes or just shoes.
Officially, CERN is presenting its evidence this week at a physics conference in Australia but plans to accompany the announcement with meetings in Geneva. The two teams, ATLAS and CMS, then plan to publicly unveil more data on the Higgs boson at physics meetings in October and December. Each of the teams involves thousands of people working independently to ensure accuracy.
The scientific threshold for discovery is high. Scientists have to show with complex formulas that there's a less than 1 in 1.7 million chance that the findings are a statistical fluke. With two independent experiments showing that there's less than 1 in 16,000 chance of being wrong, it's a matter of how their work is put together.
Scientists with access to the new CERN data say it shows with a high degree of certainty that the Higgs boson may already have been glimpsed, and that by unofficially combining the separate results from ATLAS and CMS it can be argued that a discovery is near. Ellis says at least one physicist-blogger has done just that in a credible way.
CERN spokesman James Gillies said Monday that he would be "very cautious" about unofficial combinations of ATLAS and CMS data.
"Combining the data from two experiments is a complex task, which is why it takes time, and why no combination will be presented on Wednesday." he said.
But if the calculations are indeed correct, said John Guinon, a longtime physics professor at the University of California at Davis and author of the book "The Higgs Hunter's Guide," then it is fair to say that "in some sense we have reached the mountaintop."
Sean M. Carroll, a California Institute of Technology physicist flying to Geneva for Wednesday's announcement, said that if both ATLAS and CMS have independently reached these high thresholds on the Higgs boson, then "only the most curmudgeonly will not believe that they have found it."
___
Borenstein reported from Washington.
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